Method of manufacturing a nicotine delivery product
AssigneeFertin Pharma A/S
InventorCarsten Andersen
Life of this patent
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Abstract
A method of manufacturing a nicotine delivery product comprising nicotine and a cation exchange resin. More precisely, to a method for preparing a nicotine delivery product said method comprising (a) mixing nicotine, a cation exchange resin, an organic polyol and water to form a mixture wherein the total amount of water is from 26 to 45% by weight of the total mixture, and (b) removing water from the mixture to produce said nicotine delivery product.
Claims14
A method for preparing a nicotine delivery product;
- said method comprising:
- (a) mixing an aqueous suspension of a nicotine/cation exchange resin complex with glycerol or an aqueous solution or suspension thereof forming a mixture comprising a paste, wherein the total amount of water is from 26 to 45% by weight of the total mixture;
- wherein the resin is polacrilex;
- and
- (b) removing water from the paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.
A method for preparing a nicotine delivery product;
- said method comprising
- (a) mixing an aqueous solution of nicotine with a cation exchange resin forming a nicotine/cation exchange resin complex;
- (b) admixing to said complex of step (a) an aqueous solution or suspension of glycerol to form a mixture comprising a paste, wherein the nicotine/cation exchange resin complex incorporates the glycerol and the total amount of water is from 26 to 45% by weight of the total mixture;
- wherein the resin is polacrilex;
- and
- (c) removing water from said paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.
A method for preparing a nicotine delivery product, said method comprising:
- (a) mixing an aqueous solution of nicotine with a cation exchange resin, wherein the resin is polacrilex;
- wherein the total amount of water is from 26 to 45% by weight of the total mixture;
- (b) admixing with said complex of step (a) glycerol to form a mixture comprising a paste wherein the nicotine/cation exchange resin complex incorporates the glycerol;
- and
- (c) removing water from said paste to produce said nicotine delivery product having a nicotine release rate of at least 80% over a 10 minute period.
A method for preparing a nicotine delivery product;
- said method comprising:
- (a) mixing an aqueous suspension of a nicotine/cation exchange resin complex with an organic polyol or an aqueous solution or suspension thereof forming a mixture comprising a paste, wherein the total amount of water is from 26 to 45% by weight of the total mixture;
- wherein the resin is polacrilex;
- and
- (b) removing water from the paste to produce said nicotine delivery product having a release rate of 80% or more over a 10 minute time period.
Dependencies are inferred from the claim text.