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AssigneeThe Procter & Gamble Company
InventorsTeresa DiColandrea, Robert Scott Youngquist, Sancai Xie, Robert Lloyd Binder, Gary Richard Fuentes, Deborah Lade
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The invention provides a method for improving hair biology, e.g., hair growth. The method comprises administering to a subject a monoamine oxidase inhibitor and a vasodilator, a zinc salt of a carboxylic acid, a xanthine compound, pyrithione or a salt thereof, saponin, tritapene, crataegolic acid, celastrol, asiatic acid, an inhibitor of 5-alpha-reductase, 1,4-methyl-4-azasteroid, an androgen receptor antagonist, azelaic acid or a derivate thereof, cyclosporin, triiodothyronine, diazoxide, retinoic acid, a prostaglandin analog, aminexil, carnitine tartrate, apigenin, procapil, or adenosine, in an amount effective to achieve a desired effect. The invention further provides a method of reducing or delaying the appearance of an age-related skin imperfection. The method comprises administering to the subject a composition comprising an MAO inhibitor. A kit for improving hair growth also is provided.
A method for improving hair growth in a subject in need thereof, the method comprising administering to a subject a monoamine oxidase (MAO) inhibitor selected from the group consisting of clorgiline, paragyline, lazabemide, selegiline, phenelzine, and rasagiline, and a vasodilator selected from the group consisting of minoxidil, apigenin, hydralazine, prostaglandin, and prostacyclin, in an amount effective to improve hair growth;
A kit comprising a composition comprising (a) a monoamine oxidase (MAO) inhibitor selected from the group consisting of clorgiline, paragyline, lazabemide, selegiline, phenelzine, and rasagiline, and, in the same composition or in a different composition, a vasodilator selected from the group consisting of minoxidil, apigenin, hydralazine, prostaglandin, and prostacyclin, in an amount effective to improve hair growth in a subject in need thereof, wherein the composition comprising the monoamine oxidase (MAO) inhibitor comprises from about 0.1% to about 20% of the monoamine oxidase (MAO) inhibitor, by weight of the composition, and wherein the composition comprising the vasodilator comprises from about 0.01% to about 20% of the vasodilator, by weight of the composition;
A method for improving hair growth in a subject in need thereof, the method comprising administering to a subject a monoamine oxidase (MAO) inhibitor selected from the group consisting of clorgiline, paragyline, lazabemide, selegiline, phenelzine, and rasagiline, and a vasodilator selected from the group consisting of minoxidil, apigenin, hydralazine, prostaglandin, and prostacyclin, in an amount effective to improve hair growth;
Dependencies are inferred from the claim text.