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US 8,986,612 B2Granted
HIFU induced cavitation with reduced power threshold
AssigneeBiocartis NV
InventorsArie R. Van Doorn, Michiel De Jong
Life of this patent
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Abstract
An apparatus for irradiating a liquid sample with acoustic energy to generate cavitation in the liquid sample. The apparatus includes a source for emitting high intensity ultrasound waves and is adapted to receive a cartridge having a chamber containing the liquid sample, wherein the high intensity ultrasound waves are focused on a focus position at or near a nucleation element extending at least partially into the chamber.
Claims19
A system for irradiating a liquid sample with acoustic energy to generate cavitation in the liquid sample, the system comprising:
- a cartridge having a chamber for containing the liquid sample;
- a nucleation element extending at least partially into the chamber of the cartridge, said nucleation element having a rough surface to generate a source of air bubbles that act as nucleation sites within the liquid sample contained in the chamber;
- an apparatus including:
- a receiving section for receiving the cartridge;
- a source for emitting high intensity ultrasound waves into the cartridge;
- and
- a control unit for causing the high intensity ultrasound waves to be focused on a focus position within the liquid sample in the chamber, said focus position at or near the nucleation element extending at least partially into the chamber of the cartridge;
- and
- a focusing element to focus the high intensity ultrasound waves at said focus position within the liquid sample.
6 more elements
Dependencies are inferred from the claim text.