Drug delivery device

A drug delivery device, having a body, the body comprising a resettable dose setting mechanism, a cartridge holder for receiving a cartridge containing at least one medicinal product, and a releasable coupling connecting the cartridge holder to the body or the dose setting mechanism, wherein the releasable coupling is adapted and arranged such that an initial rotational coupling movement in a rotating direction of the cartridge holder relative to the body or the dose setting mechanism causes the cartridge holder to move in a first axial direction relative to the body or the dose setting mechanism and that a continued rotational coupling movement in the rotating direction of the cartridge holder relative to the body or the dose setting mechanism causes the cartridge holder to move in a second axial direction, which is in an opposite direction compared to the first axial direction, relative to the body or the dose setting mechanism,

• wherein the releasable coupling further comprises corresponding pairs of ramps or helical features provided on respective end faces of the body and cartridge holder to move the cartridge holder in the second axial direction relative to the body or the dose setting mechanism.