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US 8,981,078 B2Granted
Selective inhibitors of translesion DNA replication
AssigneeCase Western Reserve University
InventorsAnthony J. Berdis, Irene Lee, Xuemei Zhang
Life of this patent
Estimating the term…
Abstract
An agent for inhibiting translesion DNA replication comprises a non-natural adenine ribose analog represented by those as set forth in FIG. 1.
Claims4
A method of monitoring DNA damage, comprising:
- treating cells of a patient with:
- 5 phenyl-indolyl-2′deoxyriboside, a phosphate thereof, or a pharmaceutically acceptable salt thereof;
- and
- determining the amount of the agent incorporated into the DNA of the cells.
1 more element
Dependencies are inferred from the claim text.