Method of making a vascular closure device
AssigneeCordis Corporation
InventorsVipul Bhupendra Dave, Howard Scalzo, Jerome Fischer
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Abstract
A method of making a biocompatible, implantable medical device, including a vascular closure device is disclosed. The method includes forming a biocompatible polymer into at least one fiber and randomly orienting the at least one fiber into a fibrous structure having at least one interstitial spaces. Polymeric materials may be utilized to fabricate any of these devices. The polymeric materials may include additives such as drugs or other bioactive agents as well as antibacterial agents. In such instances, at least one agent, in therapeutic dosage, is incorporated into at least one of the fibrous structure and the at least one fiber.
Claims18
A method of making a vascular closure device comprising:
- forming a biocompatible polymer into at least one fiber having a fiber matrix by
- melt spinning an absorbable polymer resin multifilament fibers with different denier and tenacity;
- applying a spin finish to the surface of the multifilament fibers;
- crimping and cutting the multifilament fibers into short staple fibers;
- providing as non-woven mat from the short staple fibers;
- rinsing the non-woven mat with solvent
- drying the non-woven mat;
- cutting the non-woven mat into a desired geometry including at least a cylindrical plug having at least one interstitial space between at least one randomly oriented fiber in the at least one cylindrical plug;
- dispersing at least one agent, in therapeutic dosage, in the fiber matrix of the at least one fiber, the agent being configured for controlled elution therefrom.
Dependencies are inferred from the claim text.