Hyperspectral technology for assessing and treating diabetic foot and tissue disease
AssigneeHypermed Imaging, Inc.
InventorsJenny E. Freeman, Svetlana V. Panasyuk, Michael J. Hopmeier, Derek Brand, Kevin Schomacker
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Abstract
This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction), obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.
Claims22
A method of applying a treatment to a tissue of a subject capable of ameliorating a disorder of the subject, the method comprising:
- (A) determining a first physiological state of the tissue by using a hyperspectral imaging device to obtain a first hyperspectral image of the tissue while said tissue is not subject to a pressure or weight;
- (B) applying a pressure or weight to the tissue;
- (C) determining a second physiological state of the tissue by using a hyperspectral imaging device to obtain a second hyperspectral image of the tissue while said tissue is subject to the pressure or weight;
- (D) identifying areas of the tissue or corresponding aspects of the pressure or weight that can be modified to reduce the difference between the first and second physiological states, wherein the identifying (D) comprises registering the first hyperspectral image to the second hyperspectral image and wherein the identifying (D) thereby specifies non-uniform application of the pressure or weight to the tissue, wherein the first and second physiologic states comprise tissue oxygenation, oxygen extraction, tissue metabolism, or tissue perfusion;
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- (E) applying a treatment regimen to the subject based on the identification of the areas of the tissue or corresponding aspects of the pressure or weight that can be modified to reduce the difference between the first and second physiological states.
Dependencies are inferred from the claim text.