# US 8,968,770 B2 · Multi-part kit comprising a chewing gum and further a flavor containing formulation > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,968,770 B2 - Document ID: US8968770B2 - Status: Granted - Kind: B2 - Application number: 13/164,637 - Filed: 2011-06-20 - Published: 2011-10-13 - Granted: 2015-03-03 - Earliest claimed: 2008-12-19 - Assignees: Fertin Pharma A/S - Applicants: Kurt Møller Pedersen; Jette Bæk Andersen - Inventors: Kurt Møller Pedersen; Jette Bæk Andersen - Web page: https://patentgrep.com/patent/US8968770B2 ## CPC - A61K 9/0058: {Chewing gums (non-medicinal aspects, preparing chewing gum A23G4/00; chewing gum for care of the teeth or oral cavity, e.g. with breath freshener A61Q11/00)} - A23G 4/06: characterised by the composition {containing organic or inorganic compounds} - A23G 4/18: characterised by shape, structure or physical form, e.g. aerated products - A23G 4/184: {products with a supported structure} - A23G 4/20: Composite products, e.g. centre-filled {, multi-layer, laminated} - A61P 25/34: Tobacco-abuse - A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D) - A23G: COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF - A61P: SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS ## Abstract A multi-part kit for administering at least one active pharmaceutical ingredient including at least one piece of chewing gum including the active pharmaceutical ingredient, the piece of chewing gum comprising gum base; and at least one further flavor-containing formulation; wherein the gum base content of the at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said piece of chewing gum. ## Claims ### Claim 1 A multi-part kit for administering at least one active pharmaceutical ingredient comprising: at least one piece of chewing gum comprising said active pharmaceutical ingredient, said piece of chewing gum comprising gum base; at least one further flavor-containing formulation; wherein said at least one further flavor-containing formulation forms a further piece separate and distinct from said at least one piece of chewing gum, wherein the gum base content of said at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said at least one piece of chewing gum; and consumer packaging comprising at least one first compartment containing said at least one piece of chewing gum and at least one second compartment containing said at least one further flavor-containing formulation. ### Claim 2 (depends on 1) The multi-part kit according to claim 1, wherein said at least one further flavor-containing formulation is free of gum base. ### Claim 3 (depends on 1) The multi-part kit according to claim 1, wherein the gum base content of said at least one further flavor-containing formulation is less than 40% by weight of the gum base content of said at least one piece of chewing gum. ### Claim 4 (depends on 1) The multi-part kit according to claim 1, wherein the gum base content of said at least one further flavor-containing formulation is more than 4% by weight of the gum base content of said at least one piece of chewing gum. ### Claim 5 (depends on 1) The multi-part kit according to claim 1, wherein at least one of said at least one further flavor-containing formulation comprises a flavor different from any flavor in said at least one piece of chewing gum. ### Claim 6 (depends on 1) The multi-part kit according to claim 1, wherein at least one of said at least one further flavor-containing formulation comprises a flavor being the same as a flavor in said at least one piece of chewing gum. ### Claim 7 (depends on 1) The multi-part kit according to claim 1, wherein said at least one further flavor-containing formulation comprises at least two formulations with different flavors. ### Claim 8 (depends on 1) The multi-part kit according to claim 1, wherein said at least one further flavor-containing formulation is a pellet. ### Claim 9 (depends on 1) The multi-part kit according to claim 1, wherein said at least one further flavor-containing formulation comprises flavor selected from the group consisting of cinnamon, wintergreen, spearmint, orange, tutti, peppermint, menthol and lemon. ### Claim 10 (depends on 1) The multi-part kit according to claim 1, wherein said active pharmaceutical ingredient is a tobacco alkaloid. ### Claim 11 (depends on 1) The multi-part kit according to claim 1, wherein a ratio of number of flavor-containing formulations and number of pieces of chewing gum of said multi-part kit is above 2. ### Claim 12 (depends on 1) The multi-part kit according to claim 1, wherein said consumer packaging comprises individually sealed compartments. ### Claim 13 (depends on 1) The multi-part kit according to claim 1, wherein said consumer packaging comprises a plastic box or a blister-package. ### Claim 14 (depends on 1) The multi-part kit according to claim 1, wherein said multi-part kit comprises at least one piece of chewing gum comprising gum base and nicotine; and one or more pieces of flavor-containing pellets comprising gum base, wherein the gum base content of said pieces of flavor-containing pellets is less than 70% by weight of the gum base content of said piece of chewing gum. ### Claim 15 An assortment of at least two multi-part kits; each of said at least two multi-part kits comprises at least one piece of chewing gum comprising at least one active pharmaceutical ingredient, and each of said at least two multi-part kits further comprises at least one further flavor-containing formulation, wherein said at least one further flavor-containing formulation forms a further piece separate and distinct from said at least one piece of chewing gum; said at least one piece of chewing gum comprises gum base; said at least one active pharmaceutical ingredient of the individual pieces of chewing gum is the same for each of the at least two multi-part kits; the at least one further flavor-containing formulation of a first multi-part kit comprises at least one flavor different from flavors of the at least one further flavor-containing formulation of a second multi-part kit; and each of said at least two multi-part kits comprises consumer packaging comprising at least one first compartment containing said at least one piece of chewing gum and at least one second compartment containing said at least one further flavor-containing formulation. ### Claim 16 (depends on 15) The assortment of at least two multi-part kits according to claim 15, wherein the gum base content of said at least one further flavor-containing formulation is less than 70% by weight of the gum base content of said piece of chewing gum. ### Claim 17 (depends on 1) An assortment of at least two multi-part kits, wherein said multi-part kits are multi-part kits according to claim 1. ### Claim 18 (depends on 1) A method of administering at least one pharmaceutically active ingredient being part of the multi-part kit of claim 1, said method comprising the steps of: administering at least one piece of chewing gum comprising said at least one pharmaceutically active ingredient, and administering at least one further flavor-containing formulation after a time interval of chewing said piece of chewing gum to maintain a satisfying taste for a longer period of time while releasing said pharmaceutically active ingredient. ### Claim 19 (depends on 18) The method of administering at least one pharmaceutically active ingredient according to claim 18, wherein the time interval between administering said at least one piece of chewing gum to administering said at least one further flavor-containing formulation is at least 15 seconds. ### Claim 20 (depends on 18) The method of administering at least one pharmaceutically active ingredient according to claim 18, wherein the time interval between administering said at least one piece of chewing gum to administering said at least one further flavor-containing formulation is at most 20 minutes. ### Claim 21 (depends on 18) The method of administering at least one pharmaceutically active ingredient according to claim 18, wherein said at least one further flavor-containing formulation is supplemented with at least one further flavor-containing formulation after at least about 3 to 9 minutes, and again after at least about 10 to 18 minutes. ### Claim 22 (depends on 18) The method of administering at least one pharmaceutically active ingredient according to claim 18, wherein said at least one further flavor-containing formulation is supplemented with at least one further flavor-containing formulation after at least about 3 to 7 minutes, again after at least about 7 to 12 minutes, again after at least about 12 to 18 minutes, and again after at least about 18 to 28 minutes. ### Claim 23 (depends on 18) The method of administering at least one pharmaceutically active ingredient according to claim 18, wherein chewing said piece of chewing gum continues for more than 5 minutes. ### Claim 24 (depends on 10) The multi-part kit according to claim 10, wherein said tobacco alkaloid is nicotine, wherein said nicotine is in a form selected from the group consisting of nicotine salts, nicotine free base, encapsulated nicotine, nicotine bound in a complex, and any combination thereof.