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US 8,962,290 B2Granted
Enhanced animal cell growth using ultrasound
AssigneeIntelligentnano Inc.
InventorsJie Chen, James Xing, Woon T. Ang, Hilal Gul
Life of this patent
Estimating the term…
Abstract
A method of increasing animal cell growth and monoclonal antibody production in an animal cell or cell culture includes the use of ultrasound at a frequency greater than about 1 MHz.
Claims18
A method of increasing the rate of growth of an animal cell culture, comprising exposing the animal cell culture to ultrasound having a frequency from greater than about 1 MHz to 2 MHz,
- wherein the ultrasound is pulsed, and
- the animal cell culture is a hybridoma cell culture or a CHO cell culture.
A method of producing antibodies, comprising exposing an animal cell culture of antibody producing animal cells to ultrasound having a frequency from greater than about 1 MHz to 2 MHz, wherein the ultrasound is pulsed.
Dependencies are inferred from the claim text.