A25 bacteriophage lysin
AssigneeAlere Scarborough, Inc.
InventorsBrion Mermer, William J. Palin, Nancy Turcotte
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Abstract
The invention relates to the identification, sequencing, and isolation of an A25 bacteriophage lysin gene that expresses a protein involved in the lysis of bacterial cells during the phage life cycle. The invention further relates to methods for lysing certain bacteria using lysin, which are useful for example in a diagnostic procedure designed to detect these bacteria.
Claims6
An isolated fusion polypeptide comprising an amino acid sequence with at least 85% sequence identity to SEQ ID NO:2 and a purification tag.
An isolated fusion polypeptide comprising the amino acid sequence of SEQ ID NO:2 and a purification tag.
A pharmaceutical composition comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of an isolated fusion polypeptide comprising the amino acid sequence of SEQ ID NO:2 and a purification tag.
Dependencies are inferred from the claim text.