Quantification method of the feature of a tumor and an imaging method of the same

An imaging method of a cysts feature of a tumor executed by a computer system including a display device, a processor, a memory, an input device, and a storage device, applying on a gray scale image consisting of a plurality of pixel points and displaying at least one tumor therein, comprising the steps of:

• (A) retrieving, by a processor, a tumor contour and a tumor contour annular region from the gray scale image, wherein the tumor contour is in the tumor contour annular region;
• (B) displaying, by a display device, the tumor contour over the gray scale image for defining a tumor inner region and a tumor external region on the gray scale image, wherein the tumor inner region is the region enclosed by the tumor contour;
• (C) calculating, by the processor, both the minimum value and the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region;
• and
• (D) defining, by the processor, a cysts imaging upper limit and a cysts imaging lower limit, imaging a cysts feature of the tumor in the tumor inner region based on said defining, and displaying, by the display device, an image pattern including the cysts feature of the tumor,
• wherein the cysts imaging upper limit is a value defined by the minimum value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region plus a multiple, not equal to one, of the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region, and the cysts imaging lower limit is the minimum value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region,
• wherein the cysts imaging upper limit is greater than the cysts imaging lower limit, and
• wherein when the gradient value of the gray scale of a pixel point in the tumor inner region is between the cysts imaging upper limit and the cysts imaging lower limit, the pixel point is defined as belonging to the cysts feature.

A quantification method of a calcifications feature of a tumor executed by a computer system including a display device, a processor, a memory, an input device, and a storage device, applying on a gray scale image consisting of a plurality of pixel points and displaying at least one tumor therein, comprising the steps of:

• (A) retrieving, by a processor, a tumor contour and a tumor contour annular region from the gray scale image, wherein the tumor contour is in the tumor contour annular region;
• (B) displaying, by a display device, a tumor contour over the gray scale image for defining a tumor inner region and a tumor external region on the gray scale image, wherein the tumor inner region is the region enclosed by the tumor contour;
• (C) calculating, by the processor, both the minimum value and the standard deviation of the gradient value of the gray scale of the plurality of pixel points in the tumor inner region;
• (D) retrieving, by the processor, a cysts region in the tumor inner region based on a threshold value defined by the minimum value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region plus a multiple, not equal to one, of the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region;
• (E) calculating, by the processor, the maximum value, the standard deviation, and the mean value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region;
• (F) quantifying, by the processor, a calcifications feature of the tumor in the tumor inner region based on a threshold value defined by the mean value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region plus a multiple, not equal to one, of the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region, and calculating, by the processor, the ratio of the region having the calcifications feature over the tumor inner region but outside the cysts region,
• wherein when one of the plurality pixel points in the tumor inner region but outside the cysts region has a gradient value of the gray scale lager than the threshold value, the pixel point is defined as belonging to the calcifications feature;
• and
• (G) displaying, by the display device, an image pattern including the calcifications feature of the tumor.

An imaging method of a calcifications feature of a tumor executed by a computer system including a display device, a processor, a memory, an input device, and a storage device, applying on a gray scale image consisting of a plurality of pixel points and displaying at least one tumor therein, comprising the steps of:

• (A) retrieving, by a processor, a tumor contour and a tumor contour annular region from the gray scale image, wherein the tumor contour is in the tumor contour annular region;
• (B) displaying, by a display device, a tumor contour over the gray scale image for defining a tumor inner region and a tumor external region on the gray scale image, wherein the tumor inner region is the region enclosed by the tumor contour;
• (C) calculating, by the processor, both the minimum value and the standard deviation of the gradient value of the gray scale of the plurality of pixel points in the tumor inner region;
• (D) retrieving, by the processor, a cysts region in the tumor inner region based on a threshold value defined by the minimum value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region plus a multiple, not equal to one, of the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region;
• (E) calculating, by the processor, the maximum value, the standard deviation, and the mean value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region based on the gradient value of the gray scale of each of the plurality pixel points in the tumor inner region but outside the cysts region;
• and
• (F) defining, by the processor, a calcifications imaging upper limit and a calcifications imaging lower limit, imaging a calcifications feature of the tumor in the tumor inner region but outside the cysts region based on said defining, and displaying, by the display device, an image pattern including the calcifications feature of the tumor,
• wherein the calcifications imaging upper limit is the maximum value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region and the calcifications imaging lower limit is the mean value of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region plus a multiple, not equal to one, of times of the standard deviation of the gradient value of the gray scale of the plurality pixel points in the tumor inner region but outside the cysts region, and
• wherein when the gradient value of the gray scale of a pixel point in the tumor inner region but outside the cysts region is between the calcifications imaging upper limit and the calcifications imaging lower limit, the pixel point is defined as the image of the calcifications feature.