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US 8,946,414 B2Granted
Processes for the preparation of dipyridamole
AssigneeGenerics [UK] Limited
InventorsDattatrey Kokane, Bindu Manojkumar, Vinayak Govind Gore
Life of this patent
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Abstract
The present invention relates to the active pharmaceutical ingredient dipyridamole. In particular, it relates to efficient processes for the preparation of dipyridamole which are amenable to large scale commercial production and provide the required product with improved yield and purity. The present invention also relates to a novel crystallization method for the purification of dipyridamole.
Claims11
A process for the preparation of dipyridamole comprising reacting 2,6-dichloro-4,8-dipiperidino-pyrimido(5,4-d)pyrimidine with diethanolamine at a temperature below 130° C.
Dependencies are inferred from the claim text.