Loading patent…
AssigneesHvidovre Hospital, The United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsJudith M. Gottwein, Troels Kasper Hoyer Scheel, Robert Purcell, Jens Bukh
Estimating the term…
The present invention relates to molecular approaches to the production of nucleic acid sequences, which comprises the genome of infectious hepatitis C virus. In particular, invention provides nucleic acid sequences which comprise the genomes of infectious hepatitis C viruses of either genotype 3a (strain S52) or genotype 4a (strain ED43). The invention therefore relates to the use of the nucleic acid sequences and polypeptides encoded by all or part of the sequences in the development of vaccines and diagnostic assays for HCV and in the development of screening assays for the identification of antiviral agents for HCV. The invention therefore also relates to the use of viral particles derived from laboratory animals infected with S52 and ED43 viruses.
An isolated nucleic acid molecule comprising a consensus sequence construction which encodes a human hepatitis C virus of genotype 3, wherein said molecule is capable of infectivity in vivo, and
Dependencies are inferred from the claim text.