Combination of selected opioids with muscarine antagonists for treating urinary incontinence
AssigneeGruenenthal GmbH
InventorThomas Christoph
Life of this patent
Estimating the term…
Abstract
Active compound combinations of compounds of group A, particularly opioids such as (+)-(2R,3R)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol or a salt thereof with a physiologically tolerated acid, and compounds of group B, particularly anti-muscarine agents such as oxybutynin or a salt thereof with a physiologically tolerated acid suitable for treatment of an increased urge to urinate or urinary incontinence. Related pharmaceutical formulations and methods of treatment of an increased urge to urinate or urinary incontinence are also provided.
Claims7
A composition of matter comprising as an admixture (+)-(2R,3R)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol or a salt thereof with a physiologically tolerated acid and oxybutynin or a salt thereof with a physiologically tolerated acid at dosages that provide a synergistic effect for the treatment of urinary incontinence.
Dependencies are inferred from the claim text.