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US 8,946,285 B2Granted
Oligomer-opioid agonist conjugates
AssigneeNektar Therapeutics
InventorsJennifer Riggs-Sauthier, Bo-Liang Deng, Timothy A. Riley
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Abstract
The invention provides compounds that are chemically modified by covalent attachment of a water-soluble oligomer. A compound of the invention, when administered by any of a number of administration routes, exhibits characteristics that are different from those of the compound not attached to the water-soluble oligomer.
Claims15
A compound having the structure
- wherein n is 1 to 30 and pharmaceutically acceptable salts thereof.
Dependencies are inferred from the claim text.