Fused ring compound for use as mineralocorticoid receptor antagonist

A compound represented by formula (I), or a pharmaceutically acceptable salt or an isomer thereof,

• wherein:
• X is CH2;
• Y1 is N;
• Y2 and Y3 are CH;
• R1 is halogen, cyano, hydroxyl, carboxyl, amino, nitro, sulfonic group, carbamoyl, C1-6alkyl, C3-8cycloalkyl, C2-6alkenyl, C5-8cycloalkenyl, C2-6alkynyl, C1-6alkoxy, C3-8cycloalkoxy, C1-6alkylamino, di(C1-6alkyl)amino, C1-6alkylthio, C1-6alkylcarbonyl, C1-6alkylcarbamoyl, C1-6alkylacylamino, C1-6alkylsulfonyl, C1-6alkylaminosulfonyl, C1-6alkylsulfonylamino, di(C1-6alkyl)carbamoyl, di(C1-6alkyl)aminosulfonyl, C1-6alkoxycarbonyl or C1-6alkylcarbonyloxy, n is 0-4, wherein R1 can be identical or different,
• said C1-6alkyl, C3-8cycloalkyl, C2-6alkenyl, C5-8cycloalkenyl, C2-6alkynyl, C1-6alkoxy, C3-8cycloalkoxy, C1-6alkylamino, di(C1-6alkyl)amino, C1-6alkylthio, C1-6alkylcarbonyl, C1-6alkylcarbamoyl, C1-6alkylacylamino, C1-6alkylsulfonyl, C1-6alkylaminosulfonyl, C1-6alkylsulfonylamino, di(C1-6alkyl)carbamoyl, di(C1-6alkyl)aminosulfonyl, C1-6alkoxycarbonyl and C1-6alkylcarbonyloxy can be optionally substituted with 1, 2, 3, 4, 5 or 6 substituents independently selected from the group consisting of halogen, cyano, hydroxyl, carboxyl and amino;
• R2a is cyclopentyl;
• R2b, R3a and R3b are respectively and independently hydrogen
• R4 is C(O)OR7 or C(O)NR8R9;
• R7, R8 and R9 are respectively and independently hydrogen, C1-6alkyl, C3-8cycloalkyl or 3-8 membered heterocyclic group, wherein R8 and R9, together with the nitrogen atom attached thereto, can form 3-8 membered heterocyclic group or oxo-3-8 membered heterocyclic group, said C1-6alkyl, C3-8cycloalkyl and 3-8 membered heterocyclic group can be optionally substituted with 1, 2, 3, 4, 5 or 6 substituents independently selected from the group consisting of halogen, cyano, hydroxyl, C1-6alkyl, pyrrolidinyl, OR10, C(O)R10, C(O)OR10, OC(O)R10, C(O)NR11R12, NR11R12, NR11C(O)R10, S(O)qR10, S(O)qNR11R12 and NR11S(O)qR10;
• R10, R11 and R12 are respectively and independently hydrogen, C1-6alkyl, C3-8cycloalkyl or phenyl, wherein R11 and R12, together with the nitrogen atom attached thereto, can form 3-8 membered heterocyclic group, said C1-6alkyl, C3-8cycloalkyl, phenyl and 3-8 membered heterocyclic group can be optionally substituted with 1, 2, 3, 4, 5 or 6 substituents independently selected from the group consisting of halogen, cyano, hydroxyl and carboxyl;
• Cy is phenyl;
• and
• q is an integer of 0-2.