Inhibitors of AkT activity

A compound of Formula (I),

• wherein:
• R41 is selected from:
• chlorine, ethyl, methyl and methoxy;
• R42 is
• where Q is nitrogen, Y is —CH— and Z is —C(R48)—, and
• R30 is selected from methyl and ethyl,
• where R48 is selected from:
• hydrogen, methyl, chlorine and bromine;
• R43 is hydrogen;
• R44 is —CH2-phenyl wherein the phenyl is substituted by one or two substituents selected from fluorine and trifluoromethyl;
• R45 is hydrogen;
• R20 is hydrogen;
• X is selected from O and S;
• and
• n is 1;
• or a pharmaceutically acceptable salt thereof.