Immunization of an individual against carcinomas and the preliminary stages thereof
OwnerMagnus Von Knebel Doeberitz, Michael Linnebacher +1inventors
InventorsMagnus Von Knebel Doeberitz, Michael Linnebacher, Wolfgang Rudy
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Abstract
The present invention relates to a pharmaceutical composition, comprising a cell cycle regulatory protein and/or an expressible nucleic acid coding for this in an amount suitable for immunization of an individual against carcinomas and the preliminary stages thereof and common auxiliary agents and/or to the use of a cell cycle regulatory protein and/or an expressible nucleic acid coding for this to immunize an individual against carcinomas and the preliminary stages thereof.
Claims4
A method for immunizing against carcinomas and the preliminary stages thereof, comprising use of an expressible nucleic acid coding for the cyclin-dependent kinase inhibitor p16 or fragments thereof, wherein the carcinomas are those of the upper respiratory tract and/or anogenital carcinomas;
- and wherein the fragment or fragments contain epitopes which can be detected by cytotoxic T cells and elicit a cytotoxic immune response.
Dependencies are inferred from the claim text.