Compositions and methods for identifying and targeting cancer cells of alimentary canal origin
AssigneeThomas Jefferson University
InventorsScott A. Waldman, Jason Park, Stephanie Schulz
Life of this patent
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Abstract
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing primary and/or metastatic stomach or esophageal cancer are disclosed.
Claims37
A method of treating an individual suspected of suffering from primary and/or metastatic stomach or esophageal cancer comprising the steps of administering to said individual a therapeutically effective amount of a composition comprising:
- i) a guanylyl cyclase C ligand;
- and
- ii) an active agent;
- wherein the guanylyl cyclase C ligand is an ST peptide, and the active agent is a therapeutic agent.
A method of treating an individual suspected of suffering from primary and/or metastatic stomach or esophageal cancer comprising the steps of administering to said individual a therapeutically effective amount of a composition comprising:
- i) a guanylyl cyclase C ligand;
- and
- ii) an active agent;
- wherein said active agent is a therapeutic agent.
A method of treating an individual suspected of suffering from primary and/or metastatic stomach or esophageal cancer comprising the steps of administering to said individual a therapeutically effective amount of a composition comprising:
- i) a guanylyl cyclase C ligand;
- and
- ii) an active agent;
- wherein the guanylyl cyclase C ligand is conjugated to the active agent, the guanylyl cyclase C ligand is an ST peptide that is ST Ia, and the active agent is a therapeutic agent.
Dependencies are inferred from the claim text.