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US 8,945,858 B2Granted
Methods and compositions for treating neurodegenerative disorders and alzheimer's disease and improving normal memory
AssigneeThe Regents of the University of California
InventorsNazneen Dewji, S. Jonathan Singer
Life of this patent
Estimating the term…
Abstract
The disclosure relates generally to neurodegenerative disorders and more specifically to a group of presenilin/G-protein/c-src binding polypeptides and methods of use for modulating signaling and progression of Alzheimer's disease.
Claims5
A method of assaying for inhibitors of Alzheimer's Disease progression comprising contacting a cell system comprising a first cell expressing βAPP and a second cell expressing PS-1 and/or PS-2 with an agent and measuring the activity of (a) Src family of tyrosine kinases, and/or (b) GoA and/or GoB interaction with PS-1 and/or PS-2.
Dependencies are inferred from the claim text.