Mechanical stability of the biomimetic coating by cross linking of surfactant polymer
AssigneeGreatbatch Ltd.
InventorsJan J. Lewandowski, Yubiao Liu
Life of this patent
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Abstract
A biomimetic surfactant polymer modified with various crosslinking embodiments is described. The crosslinking embodiments provide a biomimetic surfactant coating that is designed to resist cracking, scratching, spalling and chemical dissolution. The crosslinking embodiments comprise the use of various hydrophilic and hydrophobic functional groups. The modified biomimetic surfactant adheres to different substrate surfaces, particularly the surfaces of medical devices.
Claims29
A surfactant polymer modified with a crosslinking agent, the modified surfactant polymer comprising:
- a) at least one polymeric backbone chemically bonded to at least one hydrophilic molecular chain and at least one hydrophobic molecular chain, wherein either the hydrophilic molecular chain or the hydrophobic molecular chain comprises a hydroxyl functional group;
- b) a crosslinking agent comprising an aldehyde functional group therewithin;
- and
- c) wherein the aldehyde functional group of the crosslinking agent is chemically bonded with the hydroxyl functional group within the surfactant polymer.
A method of modifying a surfactant polymer, the method comprising:
- a) providing a surfactant polymer comprising:
- i) at least one polymeric backbone;
- ii) at least one hydrophilic molecular chain chemically bonded to the at least one polymeric backbone;
- iii) at least one hydrophobic molecular chain chemically bonded to the at least one polymeric backbone;
- and
- iv) wherein either the hydrophilic molecular chain or the hydrophobic molecular chain comprises a hydroxyl functional group;
- b) providing a crosslinking mixture comprising at least one aldehyde functional group;
- c) applying a layer of the surfactant polymer to a first surface;
- d) applying a layer of the crosslinking mixture to a second surface of the surfactant polymer;
- and
- e) heating the layer of surfactant polymer and layer of crosslinking mixture so that the aldehyde functional group of the crosslinking mixture chemically bonds with the hydroxyl functional group within the surfactant polymer.
A surfactant polymer modified with a crosslinking agent, the modified surfactant polymer comprising:
- a) at least one polymeric backbone chemically bonded to at least one hydrophilic molecular chain and at least one hydrophobic molecular chain, wherein the hydrophilic molecular chain comprises a hydrophilic functional group;
- b) a crosslinking agent comprising oxidized dextran;
- and
- c) wherein the oxidized dextran is chemically bonded with the hydrophilic functional group within the surfactant polymer.
Dependencies are inferred from the claim text.