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US 8,945,628 B2Granted
Magnetic nanoparticles
AssigneeThe General Hospital Corporation
InventorsRalph Weissleder, Hakho Lee, Tae-Jong Yoon
Life of this patent
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Abstract
A magnetic nanoparticle includes a magnetic core and a superparamagnetic outer shell, in which the outer shell enhances magnetic properties of the nanoparticle. The enhanced magnetic properties of the magnetic nanoparticle allow for highly sensitive detection as well as diminished non-specific aggregation of nanoparticles.
Claims8
A method of forming a nanoparticle, the method comprising:
- forming one or more ferromagnetic nanoparticle cores;
- and
- forming a super-paramagnetic shell on each of the one or more ferromagnetic nanoparticle cores, wherein the super-paramagnetic shell comprises a metal-oxide obtained from a metal complex solution.
Dependencies are inferred from the claim text.