Vinylic mask with peel-off effect for topical use containing high concentrations of retinoic acid
AssigneeLaboratori Farmaceutici Krymi S.P.A.
InventorsRocco Crimi, Raniero Cozzi
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Abstract
A formulation for topical use having a filmogenic (peel-off) action for professional and home use, containing high concentrations of Retinoic acid, the method of production and use thereof in the treatment of acne, wrinkles, hyperpigmentations, psoriasis and all imperfections linked to keratinization disorders. The composition also comprises octyldodecyl octyldodecanoate, and polyvinyl alcohol. The composition is in the form of a face mask (pack).
Claims13
A composition comprising retinoic acid and polyvinyl alcohol, characterized in that it contains 1-8% by weight of retinoic acid and 8-15% by weight of octyldodecyl octyldodecanoate with reference to the total weight of the composition.
A method of production of a composition comprising:
- a. combining in a vessel polyvinyl alcohol, disodium EDTA, acrylates/C10-30 alkyl acrylate crosspolymer, and propylene glycol in production water at a temperature comprised between 60 and 80° C.;
- b. preheating, in a separate vessel, 8-15% by weight of octyldodecyl octyldodecanoate with reference to the total weight of the composition to 40° C., to which 1-8% by weight of retinoic or 13-cis retinoic acid with reference to the total weight of the composition is added and homogenized with a turbine having a controlled speed;
- c. adding the mixture of step b) to the vessel of step a) with stirring;
- d. adding to the mixture of step c) salicylic acid pre-solubilized in denatured ethyl alcohol and imidazolidinyl urea pre-dissolved in deionized water;
- and
- e. constant stirring of the mixture of step d) until reaching a viscosity comprised between 15,000 and 23,000 mpa.
A composition comprising 1-8% by weight of retinoic acid, 8-15% by weight of octyldodecyl octyldodecanoate, 5-15% by weight of polyvinyl alcohol, and 10-30% by weight of denatured ethyl alcohol with reference to the total weight of the composition.
Dependencies are inferred from the claim text.