Pneumococcal Serotype 6D
AssigneeThe UAB Research Foundation
InventorsMoon H. Nahm, In Ho Park
Life of this patent
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Abstract
Disclosed is a new and emerging serotype of Streptococcus pneumoniae designated serotype 6D, and assays and monoclonal antibodies useful in identifying same. Also disclosed is a novel pneumococcal polysaccharide with the repeating unit→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→4) ribitol (5→phosphate. This new serotype may be included in pneumococcal vaccines.
Claims6
An isolated or purified antigen binding molecule that binds to a polysaccharide having the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→4) ribitol (5→phosphate};
- wherein the antigen binding molecule is an intact antibody, a Fab, Fab′, F(ab′)2 or Fv fragment thereof, a CDR portion of an antibody, or a peptide or derivative of an antibody, that binds said polysaccharide repeating unit.
A composition comprising at least one antigen binding molecule that binds to a polysaccharide having the repeating unit {→2) glucose 1 (1→3) glucose 2 (1→3) rhamnose (1→4) ribitol (5→phosphate};
- wherein the antigen binding molecule is an intact antibody, a Fab, Fab′, F(ab′)2 or Fv fragment thereof, a CDR portion of an antibody, or a peptide or derivative of an antibody, that binds said polysaccharide repeating unit.
Dependencies are inferred from the claim text.