Back to results
US 8,945,549 B2Granted
Methods of treating antinociceptive tolerance
AssigneeSaint Louis University
InventorDaniela Salvemini
Life of this patent
Estimating the term…
Abstract
The invention relates to methods for treating pain disorders including neuropathic and inflammatory pain and to methods to reduce or eliminate nociceptive tolerance induced by opiate analgesic use by administering an agent that suppresses or blocks S1P biological activity.
Claims4
A method of treating opiate-induced antinociceptive tolerance in an individual, the method comprising administering to the individual an effective amount of a drug selected from S1P receptor agonists and S1P receptor antagonists.
Dependencies are inferred from the claim text.