Degradable compounds and methods of use thereof, particularly with particle replication in non-wetting templates

A composition comprising a first molded particle type and a second molded particle type, wherein the matrix material of at least one particle type comprises

• i. a degradable compound having the structure of Formula (3),
• wherein:
• R1 and R2 are each independently selected from the group consisting of ethyl, methyl, propyl, isopropyl, butyl, and tert-butyl;
• R3 and R4 are each independently selected from the group consisting of —CH2—, —C2H4— and —C3H6—;
• each Z is an acrylate group;
• and
• n is an integer from 0 to 30;
• wherein the compound degrades under physiological conditions;
• and
• ii. a biodegradable polymer matrix, wherein the degradable compound crosslinks the biodegradable polymer of the matrix;
• wherein the at least one particle type is stable for more than 24 hours upon exposure to a pH of 7.4 or higher and is degradable in less than 2 hours upon exposure to a pH of 5.0 or lower, and
• wherein, the first particle type is different from the second particle type.