Dendrimer compositions and methods of synthesis
AssigneeThe Regents of the University of Michigan
InventorsJames R. Baker, Jr., Baohua Huang
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Abstract
The present invention relates to novel dendrimer compounds and methods of synthesizing the same. In particular, the present invention is directed to novel polyamidoamine (PAMAM) dendrimers, novel dendrimer branching units, methods for synthesizing such novel PAMAM dendrimers and functionalized dendrimers, as well as systems and methods utilizing the dendrimers (e.g., in diagnostic and/or therapeutic settings (e.g., for the delivery of therapeutics, imaging, and/or targeting agents (e.g., in disease diagnosis and/or therapy, etc.))).
Claims6
A composition comprising a compound having the following formula:
- wherein R1, R2, R3, R4 are R5,
- wherein R5 is
- a targeting agent, a therapeutic agent, a pro-drug, an imaging agent, or a trigger agent.
Dependencies are inferred from the claim text.