Method of manufacturing an implantable drug delivery system including an impedance pump
AssigneeCalifornia Institute of Technology
InventorsDerek Rinderknecht, Hasham Azizgolshani, Mortez Gharib
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Abstract
Described herein are systems, devices, and methods for the delivery of substances to, or the sampling of substances from, a patient using a portable and preferably implantable device. The substances introduced to and/or taken from the patient are preferably fluidic and are driven by a miniature pump, such as a microimpedance pump. A number of design variations are explicitly and implicitly described, such as the use of multiple pumps and multiple reservoirs for containing medicaments. Methods of manufacture of these systems and devices are also described, for instance, using molding, micromachining, or lithographic processes.
Claims5
A method of manufacturing an implantable drug delivery system including an impedance pump, comprising:
- forming a first layer of a substrate with a reservoir and a pump chamber wall on which an activation element can be mounted, wherein the pump chamber wall is operable to be displaced to generate pumping forces;
- forming a second layer on the substrate having an elongate recess connected to a plurality of elongate channels;
- coupling the first layer to the second layer such that the pump chamber wall is positioned over the elongate recess, the elongate recess and the plurality of elongate channels are covered by the first layer, and the reservoir is in communication with at least one of the plurality of elongate channels;
- and
- coupling the activation element to the pump chamber wall.
Dependencies are inferred from the claim text.