Large hole closure device

A closure device for closing an opening, the closure device comprising:

• an outer body having an exterior bottom, an outer wall, an interior wall, and an interior suture engaging bottom, the interior suture engaging bottom having a first opening extending distally through an exterior wall of the bottom of the outer body, the outer body having a first central axis and the first opening having a second central axis, the first central axis and the second central axis being offset, the outer body including a first engagement mechanism;
• and
• an inner body having an outer wall sized and configured to engage with the interior wall of the outer body, the inner body having a suture engaging bottom circumscribed by the inner wall of the outer body, the suture engaging bottom of the inner body having a second opening therethrough, the inner body including a second engagement mechanism that is complementary to the first engagement mechanism, wherein the first engagement mechanism includes first threads and the second engagement mechanism includes second threads, wherein the first engagement mechanism and the second engagement mechanism are configured to cooperate to close a gap between the interior suture engaging bottom of the outer body and the suture engaging bottom of the inner body to clamp sutures therebetween, wherein the top of the inner body is disposed below the top of the outer body when the inner body and the outer body are in a closed position with the inner body clamping sutures between the interior suture engaging bottom of the outer body and the suture engaging bottom of the inner body, wherein the inner body is threaded inside the outer body with the first opening and the second opening substantially aligned prior to deployment of the closure device;
• and wherein the first opening and the second opening are misaligned to lock the sutures after deployment of the closure device.