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US 8,940,794 B2Granted
Methods and compositions for treating Raynaud's disease
AssigneeNexmed Holdings, Inc.
InventorsDaniel W. Frank, Richard Martin, Bassam B. Damaj
Life of this patent
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Abstract
In various embodiments, methods and compositions for treating Raynaud's disease and Raynaud's phenomenon are provided. Topical administration of a semisolid composition comprising a prostaglandin E1 compound provides the desired relief of the Raynaud's disease or Raynaud's phenomenon without the possible complications of systemic administration. The semisolid composition can be administered as needed, or in a regimen of several doses per day.
Claims6
A method of treating Raynaud's phenomenon in a subject comprising:
- administering a semisolid composition comprising a total daily dose of about 0.945 mg to about 5.7 mg a prostaglandin E1 compound to a surface of an affected body part of the subject, wherein
- the subject's Raynaud's Phenomenon is secondary to systemic sclerosis, and
- the total daily dose is divided into 2-4 doses, and
- the total daily dose is administered in a regimen of separate applications over the course of 12-24 hours.
1 more element
Dependencies are inferred from the claim text.