Heterocyclic compounds and uses thereof

A compound of Formula (I):

• or an enantiomer, a mixture of enantiomers, or a mixture of two or more diastereomers thereof,
• or a pharmaceutically acceptable form thereof, wherein
• Cy is 6-membered aryl substituted by 1 occurrence of R3 and 0, 1, 2, or 3 occurrence(s) of R5;
• Wb5 is CR8 or CHR8;
• R8 is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, heteroalkyl, alkoxy, amido, amino, acyl, acyloxy, sulfonamido, halo, cyano, hydroxyl or nitro;
• B is hydrogen, alkyl, amino, heteroalkyl, cycloalkyl, heterocyclyl, aryl, or heteroaryl, each of which is substituted with 0, 1, 2, 3, or 4 occurrence(s) of R2;
• each R2 is independently alkyl, heteroalkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, alkoxy, amido, amino, acyl, acyloxy, alkoxycarbonyl, sulfonamido, halo, cyano, hydroxyl, nitro, phosphate, urea, or carbonate;
• X is —(CH(R9))z—;
• Y is —NH—C(═O)—, —C(═O)—N(R9)—, or —C(═O)—N(R9)—(CHR9)—;
• z is an integer of 1, 2, 3, or 4;
• R3 is alkyl, cycloalkyl, heterocyclyl, fluoroalkyl, heteroalkyl, alkoxy, amido, amino, acyl, acyloxy, sulfinyl, sulfonyl, sulfoxide, sulfone, sulfonamido, halo, cyano, aryl, heteroaryl, hydroxyl, or nitro;
• each R5 is independently alkyl, alkenyl, alkynyl, cycloalkyl, heteroalkyl, alkoxy, amido, amino, acyl, acyloxy, sulfonamido, halo, cyano, hydroxyl, or nitro;
• each R9 is independently hydrogen, alkyl, cycloalkyl, heterocyclyl, or heteroalkyl;
• or two adjacent occurrences of R9 together with the atoms to which they are attached form a 4- to 7-membered ring;
• Wd is
• X1, X2 and X3 are each independently C, CR13, or N;
• X4, X5 and X6 are each independently N, NH, CR13, S, or O;
• and
• wherein R10, R11, R12, and R13 are each independently hydrogen, alkyl, heteroalkyl, alkenyl, alkynyl, cycloalkyl, heterocyclyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, alkoxy, heterocyclyloxy, amido, amino, acyl, acyloxy, alkoxycarbonyl, sulfonamido, halo, cyano, hydroxyl, nitro, phosphate, urea, carbonate, or NR′R″ wherein R′ and R″ are taken together with nitrogen to form a cyclic moiety.