Back to results
US 8,940,732 B2Granted
Diagnosis of autism spectrum disorders and its treatment with an antagonist or inhibitor of the 5-HT2c receptor signaling pathway
AssigneeMassachusetts Institute of Technology
InventorsDamon Theron Page, Mriganka Sur
Life of this patent
Estimating the term…
Abstract
The invention relates to methods for diagnosis and treatment of autism spectrum disorders, particularly for autism spectrum disorders characterized by increased head size (circumference) and deficits in social behavior.
Claims11
A method for treating an autism spectrum disorder comprising
- administering to a subject in need of such treatment one or more therapeutic molecules that is an antagonist or inhibitor of the 5-HT2c receptor signaling pathway, wherein the antagonist or inhibitor of 5-HT2c receptor signaling pathway is SB242084 and wherein the said subject has a PTEN deficiency and/or SLC6A4 deficiency and/or increased circulating serotonin.
Dependencies are inferred from the claim text.