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US 8,940,701 B2Granted
Compounds for, and methods of, treating cancer and inhibiting invasion and metastases
AssigneeThe Regents of the University of Michigan
InventorDonna Livant
Life of this patent
Estimating the term…
Abstract
Invasion-inhibiting peptides comprising either a modified cysteine (where the sulfur atom is modified with a alkyl group or other suitable group), and/or b) D-amino acids, for the treatment “cancer” in humans and animals. Such peptides can be used together with other therapies (e.g. radiation) to enhance the therapeutic benefit and reduce invasiveness.
Claims15
A composition, comprising a peptide which has an amino acid sequence consisting of PX1SX2N (SEQ ID NO:5), where X1 is the D-isomer of histidine, and X2 is the D-isomer of cysteine, and P, S and N are all L-isomers.
Dependencies are inferred from the claim text.