Methods of treatment using TLR7 and/or TLR9 inhibitors
AssigneeDynavax Technologies Corporation
InventorsFranck Barrat, Robert L. Coffman, Cristiana Guiducci
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Abstract
The application relates to compositions and methods of regulating an immune response comprising inhibitors of TLR7 and/or TLR9, such as immunoregulatory polynucleotides and/or immunoregulatory compounds. The application also relates to compositions and methods for predicting and/or determining responsiveness of a disease to treatment comprising inhibitors of TLR7 and/or TLR9.
Claims33
A polynucleotide comprising a nucleotide sequence selected from the group consisting of SEQ ID NO:73, SEQ ID NO:134, SEQ ID NO:143 and SEQ ID NO:144, wherein the polynucleotide is less than 100 bases or base pairs in length.
Dependencies are inferred from the claim text.