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US 8,940,308 B2Granted
Methods for treating depression
AssigneeAllergan, Inc.
InventorsCatherine C. Turkel, Mitchell F. Brin
Life of this patent
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Abstract
Disclosed is a method for decreasing depression in a patient by local administration of a botulinum neurotoxin to the frontalis, corrugator, procereus, occipitalis, temporalis, trapezius and cervical paraspinal muscles.
Claims17
A method for treating or reducing the occurrence of depression in a patient, the method comprising:
- local administration of a botulinum neurotoxin to 31 fixed injection sites across seven head and neck muscles, and optionally up to 8 additional injection sites into three specific muscles, wherein these three muscles are subset of the seven head and neck muscles,
- to thereby treat or reduce the occurrence of depression in the patient.
A method for treating or reducing the occurrence of depression in a patient, the method comprising:
- local administration of a botulinum neurotoxin to the frontalis, corrugator, procerus, occipitalis, temporalis, trapezius and cervical paraspinal muscles of the patient that suffers from depression;
- wherein the botulinum neurotoxin is administered to the frontalis at about twenty units divided among four sites of injection;
- to the corrugator at about ten units divided among two sites of injection;
- to the procerus at about five units to one site of injection;
- to the occipitalis at about thirty units divided among six sites of injection to about forty units divided among eight sites of injection;
- to the temporalis at about forty units divided among eight sites of injection up to fifty units divided among ten sites of injection;
- to the trapezius at about thirty units divided among six sites of injection up to about fifty units divided among ten sites of injection and to the cervical paraspinal muscles at about twenty units divided among four sites of injection;
- wherein the botulinum neurotoxin is injected at 31 to 39 injection sites;
- thereby to treat or reduce the occurrence of depression in the patient.
6 more elements
Dependencies are inferred from the claim text.