Back to results
US 8,939,966 B2Granted
Differential laser-induced perturbation (DLIP) for bioimaging and chemical sensing
AssigneeUniversity of Florida Research Foundation, Inc.
InventorDavid Worthington Hahn
Life of this patent
Estimating the term…
Abstract
Methods for imaging or optical sensing of a material are provided. A first fluorescent image or optical signal of a material can be recorded, the material can be perturbed, and then a second fluorescent image or optical signal of the material can be recorded. The two fluorescent images or signals can be subtracted to give a differential image or optical signal.
Claims80
A method for imaging or sensing a material, comprising:
- irradiating a material with radiation having a first wavelength;
- recording a first image or signal from the material after irradiating the material with the radiation having the first wavelength;
- photochemically perturbing the material after recording the first image or signal from the material;
- irradiating the material with radiation having the first wavelength after photochemically perturbing the material;
- recording a second image or signal from the material after irradiating the material with the radiation having the first wavelength after photochemically perturbing the material;
- and
- determining, by a computer processor, a difference between the first image or signal and the second image or signal to give a differential image or signal.
4 more elements
A system for imaging or sensing a material, comprising:
- a radiation source, wherein the radiation source is adapted to irradiate a material with radiation having a first wavelength;
- a detector, wherein the detector is adapted to record a first image or signal from the material after the material is irradiated with the radiation having the first wavelength;
- a perturbing mechanism, wherein the perturbing mechanism is adapted to photochemically perturb the material after the detector records the first image or signal;
- wherein the radiation source is adapted to irradiate the material with radiation having the first wavelength after the material is photochemically perturbed;
- wherein the detector is adapted to record a second image or signal from the material after the material is irradiated with the radiation having the first wavelength after the material is photochemically perturbed;
- and
- a computer processor adapted to determine a difference between the first image or signal and the second image or signal to give a differential image or signal.
4 more elements
Dependencies are inferred from the claim text.