Method of treating eosinophilic esophagitis
AssigneeDBV Technologies
InventorsPierre-Henri Benhamou, Lucie Mondoulet
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Abstract
The present invention relates to the treatment of EE. More specifically, the invention relates to a new method of treating EE through the epicutaneous route. In particular, the method of the invention comprises applying to the skin of the subject a skin patch device, comprising a composition, under conditions allowing a contact between said composition and the skin. The present invention also relates to the skin patch device and to a use of the skin patch device in the manufacture of a composition for treating eosinophilic esophagitis in a subject.
Claims8
A method of treating a food-induced eosinophilic esophagitis in a subject, said eosinophilic esophagitis being characterized by an eosinophilic infiltration in the subject, the method comprising epicutaneously applying to the skin of the subject having eosinophilic infiltration a non-perforating skin patch device comprising a composition comprising, as the only active ingredient, a food allergen under conditions allowing contact between said composition and the skin, and in an amount sufficient to cause a decrease of eosinophilic infiltration in an esophagus or gut of the subject, said application resulting in a treatment of said eosinophilic esophagitis.
A method of decreasing eosinophilic infiltration in an esophagus or gut of a subject having eosinophilic infiltration, said method comprising epicutaneously applying to the skin of the subject a non-perforating skin patch device comprising a composition comprising, as the only active ingredient, a food allergen under conditions allowing a contact between said composition and the skin, said application resulting in a decrease of eosinophilic infiltration in the esophagus or gut.
Dependencies are inferred from the claim text.