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US 8,927,271 B1Granted
Compositions and methods for detecting target analytes
OwnerJack T. Johanseninventor
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Abstract
This invention is directed to compositions and methods for determining target analytes. The compositions disclosed relate to cell-linker-probe complexes. The disclosed methods (including multiplex methods) utilize said cell-linker-probe complexes for target analyte determination.
Claims10
A composition comprising an internally stained cell, a linker and a probe;
- wherein,
- a) said internally stained cell comprises a surface and a plurality of the same or different markers within said cell that internally stain said cell;
- and
- b) said linker operably links said probe to said surface of said internally stained cell such that said probe is capable of binding to a target present outside of said cell;
- wherein said probe is a nucleic acid oligomer, a nucleic acid analog oligomer, a nucleic acid mimic oligomer or chimera.
2 more elements
Dependencies are inferred from the claim text.