Method for coating inner surface of medical tube made from vinyl chloride with anti-thrombotic material

A method for coating an inner surface of a polyvinyl chloride medical tube containing a plasticizer, the method comprising, in the recited order, the steps of:

• passing a solution obtained by dissolving an antithrombogenic material in a solvent comprising water and at least one kind of alcohol that dissolves the copolymer but does not dissolve the plasticizer through the inner surface of the tube;
• passing water through the tube;
• and
• drying the tube,
• wherein an antithrombogenic material is composed of a copolymer comprising methoxypolyethyleneglycol(meth)acrylate, alkyl (meth)acrylate, and silicone(meth)acrylate, and
• the amount of the solution to be passed through the inner surface of the tube is 1 to 20% based on the gross volume of the internal cavity of the tube, and the amount of the water to be passed through the inner surface of the tube is 50 to 300% based on the gross volume of the internal cavity of the tube.

A method for coating an inner surface of a polyvinyl chloride medical tube containing a plasticizer, the method comprising, in the recited order, the steps of:

• passing a solution obtained by dissolving an antithrombogenic material in a solvent comprising water and at least one kind of alcohol that dissolves the copolymer but does not dissolve the plasticizer through the inner surface of the tube;
• passing water through the tube;
• and
• drying the tube,
• wherein an antithrombogenic material is composed of a copolymer comprising methoxypolyethyleneglycol(meth)acrylate, alkyl (meth)acrylate, and silicone(meth)acrylate, and
• the amount of the antithrombogenic material coating the inner surface of the tube is 1 to 500 μg/cm2.