Synthetic transtaganolide and basiliolide products, derivatives thereof, and synthesis methods thereof

A method of synthesizing a compound represented by Formula I, comprising:

• reacting a compound represented by Formula II with a compound represented by Formula III,
• wherein:
• Y is —O(hydrocarbyl);
• M is SnR16R17R18 wherein R16, R17, and R18 are each hydrocarbyl;
• W is —O;
• Wb is —OH or —OSiR30R31R32, wherein R30, R31, and R32 are each hydrocarbyl;
• Z is O;
• R1 is H;
• R2, R3, and R6 are each independently selected from hydrogen and hydrocarbyl;
• R4 is CH3 or CO2CH3;
• R5 is selected from hydrogen, hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, or substituted heteroatom-containing hydrocarbyl;
• and
• R7 and R8 are each independently selected from hydrogen, hydrocarbyl, substituted hydrocarbyl, heteroatom-containing hydrocarbyl, or substituted heteroatom-containing hydrocarbyl, wherein two or more adjacent R groups optionally combine to form a ring;
• under conditions sufficient to cause bond formation between a compound of Formula (II) and a compound of Formula (III) to create a coupling adduct;
• and
• contacting the coupling adduct with a proton source to form a compound of Formula (I).