Crystalline form of carbamoyl-cyclohexane derivatives
OwnerXiangmin Liao, Hiajian (Jim) Zhu +1inventors
InventorsXiangmin Liao, Hiajian (Jim) Zhu, Andreas Grill
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Abstract
The present invention relates to novel crystalline forms of carbamoyl-cyclohexane derivatives and, more particularly, to novel co-crystalline forms of trans-1{4-[2-[4-(2,3-dichlorophenyl-piperazin-1-yl]-ethyl]-cyclohexyl}-3,3-dimethyl urea hydrochloride and an acid such as fumaric acid. Processes for preparing these forms, compositions containing these forms, and methods of use thereof are also described.
Claims12
A co-crystal of trans-1{4-[2-[4-(2,3-dichlorophenyl)-piperazin-1-yl]-ethyl]-cyclohexyl}-3,3-dimethyl urea hydrochloride and fumaric acid having an X-ray powder diffraction pattern comprising characteristic peaks at about 8.3 and about 38.5±0.2 degrees 20.
Dependencies are inferred from the claim text.