mTOR selective kinase inhibitors

A compound of Formula II:

• or a salt thereof;
• wherein X is CH;
• R1is 1 ) heterocyclyl optionally substituted with C(O)OR15, C(O)R16, or S(O)2R17;
• or 2) cycloalkyl optionally substituted with OH, C(O)OR15, or R17;
• R2 is hydrogen or alkyl;
• R3 is hydrogen;
• each R4 is independently 1) alkyl;
• or 2) aryl optionally substituted with R16 or C(O)R16;
• R5 is hydrogen;
• or each R2 and R5 together with the atom(s) that each is respectively attached to can form a cyclo or heterocyclo structure;
• R15 is hydrogen or C1-C4 alkyl;
• R16 is heterocyclyl or C1-C4 alkyl, wherein each of said heterocyclyl or C1-C4 alkyl is independently optionally substituted with OH, halogen, C1-C4 alkyl, C1-C4 alkoxy, or NH2;
• and
• R17 is C1-C4 alkyl optionally substituted with OH.