Topical compositions for treatment of skin conditions

A method for treating a skin condition selected from the group consisting of acne vulgaris, cystic acne, hyper-pigmentation, dermal hypoplasia, epidermal hypoplasia, dermal keratosis, epidermal keratoses, wrinkles of the skin as an incident of aging, enlarged pores, surface roughness, ichthyoses, follicular disorders, benign epithelial tumors, perforated dermatoses, disorders of keratinization, and combinations thereof, comprising topically applying to skin affected by the skin condition a composition comprising:

• (i) at least one active agent according to the structure of Formula (I) or Formula (II)
• wherein R is:
• X is —H, —F, —Cl, —Br, —I, —OH, —OR, —OR′,
• —NO2, —NH2, —NHR′, or —NR′2;
• n is a number from 1 to 5;
• R′ is H or any of the lower alkyls ranging from C1 to C6;
• wherein R″ is
• or R′;
• R′″ is the hydrocarbon backbone of fatty acids;
• R″″ is R′ or the hydrocarbon backbone of fatty acids;
• R′″″ is the lower alkyls ranging from C1 to C6;
• and further,
• where there are two or more R′, R″, R′″, R″″, or R′″″ groups attached to the same carbon, each R′, R″, R′″, R″″, or R′″″ group may be the same as or different from the other R′, R″, R′″, R″, or R′″ groups attached to that carbon;
• (ii) an active agent according to the structure of Formula (VIII)
• or a salt thereof;
• and
• (iii) isohexadecane, polysorbate, phenoxyethanol, one or more C12-C16 alcohols, and one or more polyols.