Bacillus host cell
OwnerJens Tonne Andersen, Steen Troels Jorgensen +3inventors
InventorsJens Tonne Andersen, Steen Troels Jorgensen, Michael Dolbjerg Rasmussen, Peter Bjarke Olsen, Ib Groth Clausen
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Abstract
A Bacillus licheniformis mutant host cell derived from a parent B. licheniformis host cell, which mutant host cell is mutated in one or more gene(s) encoding one or more secreted polypeptide(s) which is at least 80% identical to one or more of the polypeptides shown in SEQ ID NO's: 2 to 248, wherein the mutant host cell secretes at least 5% less of the one or more secreted polypeptide(s) than the parent host cell, when they are cultivated under comparable conditions.
Claims25
A mutant host cell of a parent Bacillus licheniformis host cell, wherein the mutant comprises:
- (a) a mutation that results in no production of a secreted polypeptide having at least 95% sequence identity to SEQ ID NO:
- 166;
- and
- (b) a nucleic acid sequence encoding a heterologous polypeptide.
Dependencies are inferred from the claim text.