Surface independent, surface-modifying, multifunctional coatings and applications thereof
AssigneeNorthwestern University
InventorsPhillip B. Messersmith, Haeshin Lee, Andrea R. Statz, Bruce P. Lee, Jeffrey L. Dalsin, Daniel Sherman
Life of this patent
Estimating the term…
Abstract
The invention provides surface treatments that reduce or eliminate marine biofouling of various surfaces. A surface that is to be subjected to a marine environment can be treated with a mPEG-DOPA. The treated surface is thus rendered less susceptible to fouling of the surface.
Claims21
A method of spontaneously modifying a substrate surface, the method comprising contacting at least a portion of the substrate with an alkaline solution comprising an oxidant selected from the group consisting of dissolved oxygen, triethylamine, hydrogen peroxide, sodium periodate, tertiary butylhydroperoxide, organic peroxides, quinines, nitroaryl compounds, Cu2+, Fe3+, Co3+, Mn3+, phenols, indoles, and aminobenzenes;
- the solution further comprising a surface-modifying agent according to Formula I:
- wherein each of R1, R2, R3, R4 and R5 is independently selected from the group consisting of a thiol, a primary amine, a secondary amine, a nitrile, an aldehyde, an imidazole, an azide, a halide, a polyhexamethylene dithiocarbonate, a hydrogen, a hydroxyl, a carboxylic acid, an aldehyde, a carboxylic ester or a carboxamide, provided at least one of R1, R2, R3, R4 and R5 is not a hydrogen atom;
- wherein x ranges from 0 to 10 and wherein y ranges from 0 to 10, provided that x or y is at least 1;
- wherein the substrate surface is spontaneously modified.
A method of spontaneously modifying a substrate surface to provide a desired functionality, the method comprising:
- a) contacting at least a portion of the substrate surface with an alkaline, aqueous solution comprising an oxidant selected from the group consisting of dissolved oxygen, triethylamine, hydrogen peroxide, sodium periodate, tertiary butylhydroperoxide, organic peroxides, quinines, nitroarl compounds, Cu2+, Fe3+, Co3+, Mn3+, phenols, indoles, and aminobenzenes;
- the solution further comprising a surface-modifying agent according to Formula I:
- wherein each of R1, R2, R3, R4 and R5 is independently selected from the group consisting of a thiol, a primary amine, a secondary amine, a nitrile, an aldehyde, an imidazole, an azide, a halide, a polyhexamethylene dithiocarbonate, a hydrogen, a hydroxyl, a carboxylic acid, an aldehyde, a carboxylic ester or a carboxamide, provided at least one of R1, R2, R3, R4 and R5 is not a hydrogen atom;
- wherein x ranges from 0 to 10 and wherein y ranges from 0 to 10, provided that x or y is at least 1;
- and
- wherein the substrate surface is spontaneously modified;
- and
- b) contacting the surface-modified substrate with a reactive moiety, wherein the reactive moiety reacts with and is bound to the modified surface.
Dependencies are inferred from the claim text.