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US 8,911,816 B2Granted
Coating composition and use thereof
OwnerJohan Claes Wilhelm Axelsson, Fredrik Robin Lechard Liliebladinventors
Life of this patent
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Abstract
The present invention relates to a new coating composition and especially a new coating composition to be used with a specific coating device for providing an even, thin and enclosing coating on tablets, capsules or pills of different sizes and shapes in order to improve the taste and the swallowing characteristics of the tablets, capsules or pills.
Claims18
A method for coating a solid oral dosage form with a coating composition, said method comprising:
- providing a device comprising a bowl formation holding said coating composition, said bowl formation comprising an elastic diaphragm at a bottom of said bowl formation and having a penetrable opening permitting passage of said solid dosage form and
- pushing said solid dosage form through said penetrable opening to apply said coating composition to said solid dosage form
- wherein:
- said bowl formation contains a coating composition comprising 50%-93.5 weight-% of a mixture of at least two carbohydrates selected from the group consisting of a monosaccharide, an oligosaccharide, a polysaccharide, a hydrogenated monosaccharide, a hydrogenated oligosaccharide, a hydrogenated polysaccharide, and combinations thereof;
- 0.1-20 weight-% gelatine;
- 1-35 weight-% water;
- and a pH adjusting agent and
- said coating composition has a pH that differs from an isoelectric point of said gelatine by at least 2 pH units.
5 more elements
A viscoelastic coating composition for application to a tablet, a capsule, or a pill, said viscoelastic coating composition comprising:
- 50%-93.5 weight-% of a mixture at least two carbohydrates selected from the group consisting of a monosaccharide, an oligosaccharide, a polysaccharide, a hydrogenated monosaccharide, a hydrogenated oligosaccharide, a hydrogenated polysaccharide, and combinations thereof;
- 0.1-20 weight-% gelatine;
- 1-35 weight-% water;
- and
- 0.01-10 weight-% of a pH adjusting agent
- wherein said coating composition has a first elastic modulus (G′) and a first viscous modulus (G″) at 0.1 Hz in a range of between 10 and 106 Pa and a second elastic modulus (G′) and a second viscous modulus (G″) at 10 Hz frequency in a range of between 100 and 108 Pa;
- and
- said coating composition has a pH that differs from an isoelectric point of said gelatine by at least 2 pH units.
5 more elements
Dependencies are inferred from the claim text.