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US 8,911,815 B2Granted
Thin film processing apparatuses for adjustable volume accommodation
AssigneeVentana Medical Systems, Inc.
InventorsBrian Howard Kram, Kevin David Marshall, Christine Tse, Timothy James Keller, Austin Micheil Ashby
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Abstract
An apparatus can be used to apply and remove fluid substances for processing biological samples. The fluid substances can be delivered between a first substrate and a second substrate. One substrate carries a specimen. A layer of the fluid substance is retained in a gap defined by the first and second substrates. One substrate is moved with respect to the second substrate to disperse the fluid substance in the gap.
Claims22
A method of processing a sample, comprising:
- delivering a first slide carrying a first sample to a slide positioning device of an automated slide processing station;
- delivering a first liquid to at least one of the first slide and a curved portion of a roller unit of the automated slide processing station;
- and
- rolling the curved portion of the roller unit relative to the first slide held by the slide positioning device to apply the first liquid to the first sample on the first slide while the first liquid is located in a varying height gap defined by the first slide and the curved portion.
1 more element
A method of processing a sample, comprising:
- delivering a first microscope slide carrying a first sample to an automated slide processing station, wherein the automated slide processing station includes at least one thermal element configured to receive electrical energy and to generate heat for heating the first microscope slide;
- delivering a first liquid to the first microscope slide and/or a cover of a roller unit of the automated slide processing station;
- and
- rolling the cover of the roller unit along the first microscope slide to move the first liquid across the first sample while the first liquid is located in a varying height gap and while one or more of a plurality of discrete gapping elements of the cover contact the first microscope slide.
1 more element
Dependencies are inferred from the claim text.