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US 8,911,736 B2Granted
Combination therapy for treating breast cancer
AssigneeGenzyme Corporation
InventorsJay Harper, Scott M. Lonning, Frank James Hsu
Life of this patent
Estimating the term…
Abstract
The invention provides compositions and methods for treating breast cancer. Specifically, the invention relates to administering a Transforming Growth Factor beta (TGFβ) antagonist in combination with capecitabine and ixabepilone to treat breast cancer.
Claims28
A method for treating a breast cancer in a subject, the method comprising:
- administering to said subject a therapeutically effective amount of a Transforming Growth Factor beta (TGFβ) antagonist in combination with capecitabine and ixabepilone, wherein the administration of said TGFβ antagonist enhances the efficacy of capecitabine and ixabepilone to treat said breast cancer.
A method for inhibiting a breast cancer associated tumor growth in a subject, the method comprising:
- administering to said subject a therapeutically effective amount of a Transforming Growth Factor beta (TGFβ) antagonist in combination with capecitabine and ixabepilone, wherein the administration of said TGFβ antagonist enhances the efficacy of capecitabine and ixabepilone to inhibit said breast cancer associated tumor growth.
Dependencies are inferred from the claim text.