Micro-needle device
AssigneeHisamitsu Pharmaceutical Co., Inc.
InventorsTetsuji Kuwahara, Seiji Tokumoto, Kazuya Machida
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Abstract
An object of the present invention is to efficiently inject a drug (physiologically active substance). Therefore, a micro-needle device 1 comprises a base plate 2 and a micro-needle 3 installed on the base plate 2. A coating agent containing the physiologically active substance is coated at least at a part of the micro-needle 3, and a coating range thereof is 100 to 230 μm including the top of the micro-needle 3. A load due to the energy of 0.2 to 0.7 J/cm2 is applied to the micro-needle device 1 which is in contact with the skin.
Claims1
A method for injecting a physiologically active substance to a patient's skin with a micro-needle device, comprising:
- determining a suitable injection site on a patient in need of administration of the physiologically active substance,
- preparing or obtaining a micro-needle device with micro-needles installed on a base plate, wherein
- the length of the micro-needles is 300 to 550 μm,
- a coating agent containing the physiologically active substance is coated at a part of the micro-needles, and
- a coating range of the coating agent is 100 to 230 μm in height including the top of the micro-needles,
- and injecting the physiologically active substance at the injection site by applying, at least twice, a load due to the energy of 0.2 to 0.7 J/cm2 to the micro-needle device with the micro-needles in contact with the patient's skin.
Dependencies are inferred from the claim text.