System for intraluminal travel within living vasculature

A vascular microcatheter, comprising:

• a lumen having a distal end and a proximal end and a liner within the lumen;
• one or more marker bands circumferentially arranged around the lumen;
• a support structure extending from the proximal end of the lumen to the most distal marker band;
• a top jacket positioned annularly with respect to the lumen, comprising five durometers of material wherein softer materials are positioned distally, wherein the support structure and top jacket alternate along the length of the vascular microcatheter, and further comprising a lubricious coating that includes an opacifying material in a concentration of about 1 to 45% effective for tracking the vascular microcatheter through vasculature and an echogenic coating on the distal end of the lumen, the vascular microcatheter further comprising a distensible distal balloon wherein the distensible distal balloon comprises a radiopaque coating and a distal echogenic coating.